Souvik Maiti is research faculty at CSIR-IGIB, Delhi. He completed PhD (1999) from the CSIR-IICT, Hyderabad and following a postdoctoral training in USA and France, joined CSIR-IGIB (2003). He works in the area of chemical biology of nucleic acids and employs the principles of chemistry and biology to address questions of importance in biology and medicine. He is the recipient of many awards including the CSIR-Young Scientist Award, the NASI-Scopus Young Scientist Award, the AVRA Young Scientist Award in Chemistry, the Swarnajayanti Fellowship in Biological Sciences, the Shanti Swarup Bhatnagar Prize in Chemical Sciences (2014), and the DBT-National Bioscience Awards for Career Development (2016). He was elected a Fellow of the Indian Academy of Sciences in 2013.
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RNA G-quadruplex: Re-Search
RNA G-quadruplexes in untranslated regions (UTR) are known to play an important role in translational regulation. The classic G-quadruplex motif consists of a continuous array of 3–4 guanine residues with an intermittent loop size of 1–7 nucleotides (G3−4N1−7G3−4 N1−7G3−4N1−7G3−4). Investigating the possibilities of formation of RNA G-quadruplex with a stretch of sequence deviating from this classic motif will add to the overall conformations of RNA G-quadruplex bestowing diversity to this structure. In this presentation, the speaker will discuss the possibilities of unusual combinations of guanine residues involved in RNA G-quadruplex formation in the 50 UTR of different genes.